IgG inhibition of a monoclonal antibody therapy can help with the selected deactivation of serum IgG with EndoS. Peptide glycosylation can be achieved using a two-step process involving EndoA or ...

Changes in glycosylation are often associated with ... intracellular sialic acid levels is untenable by current lectin or antibody methods. In a cellular model system these mutations can be ...

New research from the Florida State University Department of Chemistry and Biochemistry shows that a particular type of monoclonal antibody known as NISTmAb retains its structure even if the sugar ...

Bleiholder's team confirmed that structural variations among antibody populations are not influenced by glycosylation—a process in which sugar molecules attach to other molecules. The research ...

Most individuals infected with HIV-1 develop neutralizing antibodies (Nab) capable of eliminating autologous ... and primarily involved changes in N-linked glycosylation. In addition, they showed that ...

From left, Florida State University faculty researcher Fanny C. Liu and Christian Bleiholder, a professor in the Department of Chemistry and ...

The anti-TA-MUC1 is the antibody contained in DS-3939 ... MUC1 is a tumor-specific transmembrane glycoprotein with aberrant glycosylation due to changes of the expression patterns of some ...

The development of first-generation recombinant therapeutic proteins through genetic engineering and the production of therapeutically effective monoclonal antibodies (mAbs) are considered major ...

The anti-TA-MUC1 is the antibody contained in DS-3939 ... TA-MUC1 is a tumour-specific transmembrane glycoprotein with aberrant glycosylation due to changes of the expression patterns of some ...