These chains are interconnected by disulfide bonds, resulting in a characteristic Y-shaped structure with a total molecular weight of approximately 150 kDa. Each antibody molecule possesses ...

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments for diseases such as cancer, Alzheimer's disease, autoimmune disorders and ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell.