Many challenges will have to be faced in the next decade to bring more efficient and affordable antibody-based drugs to the clinic. Here, we discuss strategies to select the best therapeutic ...

In 2021, five out of the top 10 selling drugs were mAbs and this trend ... when the first ever computationally designed antibody created by Israel-based Biolojic design entered clinical trial ...

Antibody drugs have reshaped how we treat diseases ... researchers rely on functional screening methods, such as cell-based assays or in vitro reconstituted systems that mimic target pathways.

The drug, called Datroway (datopotamab deruxtecan), is approved for patients who have already received endocrine-based ...

The whole P-cadherin/antibody/drug complex is then sent to a structure called the lysosome to be broken down. “Our results establish an outside-in signaling mechanism that provides fundamental ...

New York, United States, Jan. 22, 2025 (GLOBE NEWSWIRE) -- ADCs, or antibody-drug conjugates, are chemotherapeutic agents explicitly designed to treat cancer cells. Antibody-drug conjugates ...

Leap Therapeutics (LPTX) lost 63% after announcing it will not run a Phase 3 trial for its lead asset sirexatamab in gastric cancer. Read more here.

Trials in China usually recruit patients faster than in the west because of the country’s large pool of people who have not yet taken drugs for their condition and who are keen to participate in ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

Ouro launched to develop antibody drugs for chronic inflammatory conditions ... "KeyMed partners with US-based biotech Prolium in bispecific antibody deal" was originally created and published ...

Keymed Biosciences has been a prominent player in the growing trend of China-based biotech companies ... Ouro launched to develop antibody drugs for chronic inflammatory conditions and plans ...