The chimeric BCR–ABL oncoprotein is the molecular hallmark of chronic myelogenous leukemia (CML). BCR–ABL contains nuclear import and export signals but it is localized only in the cytoplasm ...

Integrative Analyses Reveal the Functional and Genetic Associations of Gene Fusions in Cancer. submitted; 2009. Wu SQ, Voelkerding KV, Sabatini L, Chen XR, Huang J, Meisner LF. Extensive amplification ...

IL-3 protects p210 Bcr-Abl-transformed 32D and Baf3 cells from apoptosis induced by Bcr-Abl tyrosine kinase inhibitors During our preliminary studies with PD180970, we found that the viability of ...