Studies performed during the past 2 years have provided a deeper understanding into the role of CTLA-4, which is expressed ... based therapeutics such as abatacept for rheumatic diseases.

The efficacy of abatacept is shown in treatment of juvenile idiopathic arthritis-related uveitis, refractory to TNF inhibitors. IFN-α2a is effective for Behçet's disease-related uveitis ...