Kaneko’s group demonstrated a reliable large-scale feeder-free production ... hematopoietic stem cells (HSCs) in the presence of cytokine cocktails that activate Notch signalling and cell ...

NOTCH1 pathway activation contributes to the pathogenesis of over 60% of T-cell acute lymphoblastic leukemia (T-ALL). While Notch is thought to exert the majority of its effects through ...

Researchers at UC Merced have used fruit flies to uncover a cellular process common to many organisms that could dramatically ...