How do DNA repair mechanisms detect and repair damaged DNA, and what happens when they fail? Defects in DNA repair underlie a number of human genetic diseases that affect a wide variety of body ...

"This basically increases energy in the body and helps repair DNA," Love shares. As NAD+ levels naturally decline with age, NR supplementation helps replenish this critical molecule, supporting ...

Whenever a cell divides -- whether to repair damaged tissue, replace old cells, or simply to help the body grow -- DNA is copied to ... "What I love about this work is that it's all about the ...

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

PARylation is integral to many key cellular functions, including signaling modulation and DNA repair. PARylation is reversible and is undone by PAR erasers such as poly ADP-ribose glycohydrolase (PARG ...