Stanford scientists have identified 380 key genetic variants that significantly influence cancer development, filtering ...

Guarding genes against damage is a crucial and complex job, so it’s to be expected that cells have several mechanisms to repair DNA breakages, each providing support under different circumstances.

The DNA repair and replication pathways converge on a common final step in which the continuity ... Ligation depends on magnesium and a high-energy cofactor, either ATP or NAD +. The reaction ...

Hypoxic cells can acquire a mutator phenotype that consists of decreased DNA repair, an increased mutation rate and increased chromosomal instability. Defects in homologous recombination and ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk.

NAD+ is the coenzyme that restores energy and radiance to your skin. With the right nutrition, a tailored routine, and ...

neurons vary in their energy requirements. As the first study to integrate cell type– and brain region–specific features of DNA repair in normal brains, this work sets a benchmark for the ...

PARylation is integral to many key cellular functions, including signaling modulation and DNA repair. PARylation is reversible and is undone by PAR erasers such as poly ADP-ribose glycohydrolase (PARG ...

Tis supplements promise energy and skin benefits, but science is still uncovering the truth about their real impact on aging.

In the pursuit of optimal health and wellness, many people are turning to intravenous (IV) therapies. Among the most popular ...