Pandey A*, Harvey BM*, Lopez MF, Ito A, Haltiwanger RS#, and Jafar-Nejad H#. Glycosylation of specific Notch EGF repeats by Ofut1 and Fringe regulates Notch signaling in Drosophila (2019). Cell ...

Three groups have now shown that the tumour suppressor gene lethal (2) giant discs (lgd) is required for correct trafficking of proteins, such as the Notch receptor, through this pathway.

The fruit fly, Drosophila, has been used by scientists ... including the Hedgehog, Notch and Hippo pathways. In a new study, published in Developmental Cell, Monash University researchers in ...