Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single molecules may have ...

The Synapse Diversity and Specificity Regulation Research Team at DGIST has profiled the molecular code that constitutes brain neural circuits and discovered that it regulates specific excitatory ...

The ultimate effect of a signal from one neuron on the next neuron depends on the function of the synapse, which is based on the type of neurotransmitter released. Excitatory synapses send signals ...

Because of dendritic filtering, distant synapses should have less efficacy than proximal ones. To investigate this, we characterized the amplitude and kinetics of excitatory synaptic input across ...

Aberrant synapse development can have pathological consequences for circuit function as demonstrated by the manifestation of devastating neurological impairments, including epilepsy and autism ...

Minghua Wu from Central South University, China, says, "In this review, we mainly discuss the effects of LRRC4 on memory by promoting the formation of excitatory synapses and long-term ...

Using eMAP researchers labeled protein components on both the presynaptic side (bassoon) and post-synaptic side (PSD-95) of an excitatory synapse in a mouse. Disclaimer: AAAS and EurekAlert!

In mice, it peaks during the first week after birth. This period coincides with the time when excitatory synapses mature following experience-driven activity. Various causes of alteration in 5-HT ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...