To understand how oxygen regulates cell proliferation at the level of gene expression, we harvested medium conditioned by G 0 fibroblasts under 2.5% oxygen. This conditioned medium increased the ...

Thus, an emerging strategy for the treatment of those conditions is to inhibit cellular proliferation by targeting cell cycle regulation. Here we will review the current understanding of the ...

The migrated fibroblasts begin to synthesise collagen around day 5. Initially, these collagen fibres are randomly orientated. Tenocytes become the main cell type, and over the next five weeks collagen ...

The small-molecule discovery could help in overcoming cell culture bottlenecks such as rapid degradation and high production costs.

Malignancy Spectrum, a cutting-edge journal dedicated to advancing the field of oncology, presents its latest issue, Volume 1, Issue 4. This issue ...

Myeong-Hwa Song. The team has unveiled an innovative technique to convert fibroblasts—common connective tissue cells—into mature and functional induced cardiomyocytes (iCMs). Their method ...

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the ...

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion.