A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in ...

lead to a range of human neuromuscular and ophthalmologic diseases. Loss of function of the TLS polymerase Pol η leads to xeroderma pigmentosum-variant, a DNA repair and cancer predisposition ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Huntington's disease is a neurodegenerative disorder that is usually fatal about 15 to 20 years after a patient is diagnosed. It is known ... | Genetics And Genomics ...

This process results in offspring with an inherited defect in DNA repair, which, depending on the genetic characteristics of the transmission, will either be expressed as a disease phenotype or ...

Any recent text book of neurology will list at least 200 neurological disorders, with diverse etiologies and genetic characteristics. A number of these disorders have a definitive link to an ...

Less than a month after researchers unveiled that a “ticking DNA clock” is behind Huntington’s disease (HD), scientists have ...

From understanding hereditary diseases to predicting drug responses, sequencing helps researchers uncover the subtle language ...

But in the case of people with Huntington’s disease, some of these helper proteins may be attacking and destabilizing not viruses but the patients’ own DNA. This happens in parts of human DNA ...

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed ... and its relationship to health and disease. The new map, appearing today in ...

The most complex engineering of human cell lines ever ... the basic building blocks of DNA and RNA. Structural variants are associated with developmental diseases and cancer.