IgG activates complement, and binds Fc-receptors (FcRs) on macrophages and neutrophils, upon which pathogens coated with IgG are phagocytosed by these cells. 14 Intriguingly, obesity is associated ...

A breakthrough discovery in enzyme science could revolutionize the treatment of autoimmune disorders and other diseases tied to the overactivity of antibodies. Published in the journal, ...

Although the polymeric immunoglobulin receptor, which also binds IgM and ... Azuma, Science University, Tokyo), and human IgM-Fc (Rockland, Gilbertsville, PA) were used. Monoclonal antibodies ...

Thus, candidates should be tested against a panel of receptors at the time of antibody engineering. ACROBiosystems provides an extensive collection of recombinant Fc receptor proteins, which ...

IgG is the most abundant type of immunoglobulin in the extracellular fluid. Its ability to bind Fc receptors on phagocytic or other lytic effector cells enables the initiation of antibody ...

Fc receptor modulators and immunoglobulin G (IgG) levels, pathological markers, and electrophysiological and imaging measures ...

The Vivacity-MG3 study is currently in its open-label extension phase, which is investigating the longer-term safety and ...