Researchers have identified a key role microglia play in melanoma brain metastases progression and mechanisms to target them.

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...

Wu and colleagues confirmed that cultured-microglia-carrying lipid droplets struggled with phagocytosis, poorly engulfing ...

Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small ...

Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small fragments called micronuclei produced by neuronal nuclei are released into ...

Microglia, the brain's immune cells, exhibit altered gene expression and a weakened immune response as they age, potentially contributing to neurological disorders like Alzheimer's and Parkinson's.

Rutgers researchers discovered that microglia from individuals with a high genetic risk for alcohol use disorder (AUD) are more active after alcohol exposure, pruning more neural connections.

The study, published today in Cancer Cell, demonstrates that microglia, a type of resident immune cell in the brain, can be ...

The team published its study “The microglial response to inhibition of Colony-stimulating-factor-1 receptor by PLX3397 differs by sex in adult mice” in Cell Reports. “It is a fortuitous ...

Pexidartinib or PLX3397 is an enzyme inhibitor commonly used to remove microglia in the lab setting to help researchers better understand the role of these cells in brain health, function ...