microglia and lymphocytes to pro-inflammatory signalling molecules. The nuclear receptor co-repressor (NCoR) and silencing mediator of retinoic acid and thyroid hormone receptors (SMRT ...

"We do not yet know why the microglia are acting differently in the two sexes. I think we'd like to understand how the signaling through this receptor is regulated in different conditions ...

We do not yet know why the microglia are acting differently in the two sexes. I think we'd like to understand how the signaling through this receptor is regulated in different conditions ...

First author Linh Le, PhD (‘24), currently a Research Scientist, SetPoint Medical Corp, was a graduate student in the Majewska Lab when she found the expected response from microglia to PLX3397 in ...

Linh Le, Ph.D., currently a Research Scientist, found the expected response from microglia to PLX3397 in male mice—it blocked the receptor that signals microglial survival and depleted the ...

Specifically, the toll-like receptor 4 appears to be a site at which drugs of abuse activate microglia. Toll-like receptor 4 activation consequently produces an innate immune response in the brain ...

This procedure reduced both amyloid deposition and levels of inflammatory microglia. When another cohort of OVX-treated mice were later given estradiol in their drinking water to restore estrogen ...

“We do not yet know why the microglia are acting differently in the two sexes. I think we'd like to understand how the signaling through this receptor is regulated in different ...