They also remove plaques and prune dysfunctional synapses between neurons. Microglia eliminate their targets by eating them: they envelope material and seal it in bubble-like organelles called ...

Microglia are immune cells in the central ... They remove damaged or unnecessary neurons, prune synapses during development ...

Changes in synapse number, proteins involved in synaptogenesis, and axon outgrowth may lead to imbalances in excitation and inhibition, and improper connectivity between specific brain regions. Recent ...

Microglia’s stress response drives toxic lipid production linked to Alzheimer’s progression. Blocking stress or lipid pathways reversed synapse loss in preclinical Alzheimer’s models. Findings ...

Her favorite projects involve sharing the insights of science and medicine. View Full Profile. Learn about our Editorial Policies. Microglia, the brain’s primary immune cells that prune extra synapses ...