The first generation of mAbs, unveiled in 1975 (ref. 1), were murine mAbs derived from mouse B-cell hybridomas (see “Monoclonal antibodies by design”). However, as murine mAbs moved into ...
examined the efficacy of two novel anti-osteopontin monoclonal antibodies (mAbs; 23C3 and F8E11) in the treatment of murine collagen-induced arthritis (CIA), an animal model of human RA.
[17] Their method followed a simple principle: fusion of spleen cells from a mouse immunized with an antigen of interest with nonsecretory murine ... clinical monoclonal antibody trials in MS ...
However, research has been hindered by a lack of effective markers and monoclonal antibodies to accurately ... stromal cells within optically cleared murine bone hemisections.
Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to ...
In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone marrow’s intricate structure, focusing on leptin receptor-expressing (LepR+ ...
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