The first generation of mAbs, unveiled in 1975 (ref. 1), were murine mAbs derived from mouse B-cell hybridomas (see “Monoclonal antibodies by design”). However, as murine mAbs moved into ...

The inhaled monoclonal antibody IN-006 shows promise in COVID-19 treatment, with high airway antibody levels and a favorable safety profile in healthy adults.

examined the efficacy of two novel anti-osteopontin monoclonal antibodies (mAbs; 23C3 and F8E11) in the treatment of murine collagen-induced arthritis (CIA), an animal model of human RA.

[17] Their method followed a simple principle: fusion of spleen cells from a mouse immunized with an antigen of interest with nonsecretory murine ... clinical monoclonal antibody trials in MS ...

However, research has been hindered by a lack of effective markers and monoclonal antibodies to accurately ... stromal cells within optically cleared murine bone hemisections.

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments ...

In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone marrow’s intricate structure, focusing on leptin receptor-expressing (LepR+ ...

"The development of a novel monoclonal antibody and a knock-in reporter allele ... Deep imaging of LepR+ stromal cells in optically cleared murine bone hemisections. Bone Research.