We know that HSV-1 first infects mucosal membranes around the mouth (hence the cold sores) or genitals before effectively setting up camp in clusters of nerve cells called peripheral ganglia.
Previous research has established that, when a peripheral neuron’s axon is severed, it decreases its synthesis of a number of proteins involved in neurotransmission and increases its synthesis of ...
In the dorsal root ganglia, where the cell bodies of the injured neurons are located, the role of macrophages is less defined. By understanding the mechanisms in place that support axonal regeneration ...
Intraneural ganglion cysts (INGCs) are benign, fluid-filled sacs that develop within the epineurium of peripheral nerves, often leading to various neurological symptoms. These cysts can arise from ...
Idiopathic Parkinson’s disease (IPD) is a central nervous system disorder affecting the basal ganglia that is caused ... thought classically to spare the peripheral nervous system, an ...
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