Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

The path of primordial germ cells illustrates the complexities of imprinted DNA, which contains epigenetic marks that turn on and off when necessary. Differences between the maternal and paternal ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...

In the intricate science of reproduction, the creation of offspring has long relied on the union of sperm and eggs, whether ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop into sperm and eggs, are formed. In six to 10 weeks after fertilization, PGCs differentiate into pro ...

The dodo bird project has hit other major milestones, as well. Colossal intends to edit the primordial germ cells (PGCs) of Nicobar pigeons, the dodo’s closest living relative, into dodos.

Germline development is the development of the cell lineage that gives rise to the reproductive cells, called gametes, of sexually reproducing organisms. Primordial germ cells, the founder cells ...