Strategies to optimize structures A detailed knowledge of antibody structure and activity now allows researchers to engineer primary antibodies on a more rational basis. This can yield more ...

Instead of phage display, its rational affinity maturation platform ... robust engineering technology underpinning bi-specific antibody design. The team has developed a knobs-into-holes (KIH ...

"Our model captures the kinetics and dynamic complexities of placental antibody transfer in ways ... modeling approach paves the way for the rational design of maternal vaccines and personalized ...

The introduction of rational design, based on detailed structural ... The discovery of adjuvants has historically been guided ...

A review of recent trends and remaining challenges in bispecific antibody (bsAb) production has been published.