45 it is attractive to speculate that they also participate in maintaining stem cell niches in the heart. Thus, their interaction with endogenous cells represents a comprehensive cell–cell ...

Figure 2: Stromal cells in the haematopoietic-stem-cell niche. The effects of MSCs on immune ... from the multipotentiality of MSCs towards their possible regulatory effects on immune cells ...

The local stem cell environment (niche) is vital for stem cell maintenance and function in many tissues, and tenascin C in particular has been shown to play an important role within stem cell niches ...

Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia.

BM stem cells reside in niches, specialized microenvironments, where they interact with various cellular and molecular components to regulate their functions. Different types of BM niches have ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Aging is inevitable for most cell types in the human body, but hematopoietic stem cells (HSCs) seem to defy the process. They retain their self-renewing ability almost throughout an organism’s ...

We investigate how stem cells perceive environmental changes and determine their cell fate, and how niches form and remodel the local environment during lung development, regeneration and disease. To ...

Med is proud to announce a strategic partnership with an FDA-approved laboratory in the field of regenerative medicine. This ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Three Georgia companies and their principals have been ... of California Davis whose blog in The Niche tracks scientific developments in stem cell research as well as misinformation and treatment ...

Liquid-liquid interfaces to mimic mesenchymal stem cell niches in the bone marrow Both the mechanical properties of the environment and the interaction with cells in the niche play a pivotal role in ...