The discovery of a protein’s contribution to the development of T-cells in the spleen and thymus could lead to new treatment strategies for immunodeficiency diseases. Despite its name ...

suggesting the organ was essential specifically for the development of the immune system. This was the first demonstration that the thymus had an immunological function, and led to further work by ...

“Our discovery—the regulatory T cell recirculation back to the thymus—promotes repair through a process that hasn’t been described before and represents a novel pathway to regeneration ...

Such intrathymic progenitors could produce RTE soon after HSCT, whereas donor-derived T-cell progenitors would require more time to populate the recipient thymus and provide production of new ...

The team’s study results, published today in the journal Immunity, outline their discovery of a specific type of regulatory T cell that can home back into the thymus and repair the organ when it's ...

The organoids, derived from mouse thymus tissue ... In the body, immature T cells acquire and lose these molecules in a specific order during their development. This corresponded nicely with ...

Researchers from the Wellcome Sanger Institute and their collaborators at Ghent University, Belgium, the National Institutes of Health's National Institute of Allergy and Infectious Diseases and ...

He uses mouse models to study the thymus, the organ in which specialized immune cells called T cells mature. His goal is to apply his findings to develop new therapies to promote immunity in cancer ...