TREM2 ligand Amyloid, which is well-studied, is a crucial pathogenic protein in Alzheimer’s disease. B7-H3, a well-studied TLT-2 ligand, is essential for adaptive immune responses. The ...
The phase 1 trial enrolled 115 people to test single and multiple ascending doses of the oral, once-daily TREM2 agonist VG-3927. Vigil included an elderly cohort and a single dose arm of 11 ...
F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have divulged triggering receptor expressed on myeloid cells 2 (TREM2) agonists reported to be useful for the treatment of amyotrophic lateral ...
【导读】TREM2是一种主要在髓样细胞表面表达的受体，是病理诱导免疫信号传导中的一个主要枢纽基因。然而，其在肝细胞癌（HCC）中的功能仍存在争议 ...
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