Humans do not express urate oxidase, but species that do express it tend to have low urate levels, so Garson et al. developed a polyethylene-glycol-modified recombinant mammalian urate oxidase ...

These can include: Xanthine oxidase inhibitors (decreases the production of urate) Uricase (breaks down urate to make it easier for the body to flush it out) Uricosuric agents (increase amount of ...