The study is published in Nature. Focusing on PKA and dephosphorylation enzymes, the research group created comprehensive gene knockout mice and conducted further experiments inducing the ...

PKA relays the message to the appropriate domain, whether it's telling a specific gene to produce more protein or stimulating ...

Protein kinases such as PKA and PKC catalyze the transfer of phosphate ... These phosphorylation reactions control the activity of many enzymes involved in intracellular signaling pathways.

The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated ... which fan out and activate protein kinases (PKA, in this example).