细胞移植疗法的临床应用需要一种非侵入性监测患者体内这些细胞的方法。 几种成像方式，包括 MRI、生物发光成像和正电子发射断层扫描，已被用来追踪体内的干细胞。 对于 MR 成像，细胞中预先装载有分子或颗粒，可显着改变图像亮度； 最常见的此类标记 ...

我们描述了一种基于慢病毒的基因传递方法，可将非天然氨基酸稳定地掺入神经干细胞表达的蛋白质中。 转导的细胞以与野生型细胞相同的方式分化成神经后代。 通过将荧光非天然氨基酸掺入电压依赖性膜脂质磷酸酶中，我们证明这种非天然氨基酸光学报告 ...

我们的目标是发现一种治疗方法，尝试使用基因修饰的造血干细胞来治疗和潜在治愈艾滋病毒感染，以增强针对艾滋病毒的免疫反应。 冲击 这项研究将为艾滋病毒感染提供一种潜在的治愈方法，但目前这种方法尚不存在。 这将消除终生服用抗病毒药物的需要。

评估结膜上皮细胞标记物（细胞角蛋白 13）的表达，作为角膜缘干细胞缺陷的诊断测试。 据观察，角膜表面至少有 16 个该标记物呈阳性的细胞可能表明角膜缘干细胞缺陷的阳性诊断。 科学摘要： 目的：本研究的目的是评估角膜表面细胞角蛋白（K）13的表达，并 ...

Solid tumors include cancers of the brain, ovary, breast, colon and other tissues. Many people believe that one quality solid tumors share is a reliance on cancer stem cells. These cancer stem cells ...

What is the California Institute for Regenerative Medicine (CIRM)? CIRM, California’s Stem Cell Agency, was created by the voters of California in 2004 when they overwhelmingly passed Proposition 71, ...

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and ...

HIV, or the human immunodeficiency virus, is a virus that infects cells of the immune system, undermining the body’s ability to fight infection and disease. Eventually infection can lead to symptoms ...

South San Francisco, CA, January 30, 2025 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has awarded nearly ...

CIRM is committed to accelerating the development of new stem cell-based therapies for chronic, debilitating diseases and disorders. The following pages describe CIRM’s stem cell research funding and ...

Many stem cell clinics, both in the U.S. and in other countries, advertise cures for a price. Understand the concerns over stem cell tourism and what CIRM is doing to bring real cures to patients who ...