Apoptosis occurs in a wide range of human diseases. In animal models of virus-induced disease, apoptosis correlates with viral titre and can be found in areas targeted by viral infection, which ...

For example, CD4/CXCR4-expressing T cells that interact with cells expressing HIV-1-encoded envelope glycoproteins first manifest autophagy and then apoptosis. In this model, depletion of beclin-1 ...

Background and objectives Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of ...

Moreover, the optimal protective agent for preventing or mitigating cisplatin-induced ototoxicity has yet to be identified. This review summarizes the current understanding of the roles of apoptosis, ...

In this study, utilizing zebrafish as a model organism, we found that OTA exerted suppressive effects on innate ... By constructing a comprehensive molecular profile, we found a significant ...

Beside developmental abnormalities, it may lead to tumorigenesis, autoimmunity, and other serious health problems. Deregulated apoptosis may also be the leading cause of cancer therapy chemoresistance ...

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...

Danés, principal investigator of the Cancer and Stem Cell Biology Lab at the Champalimaud Foundation, in Lisbon, has shown for the first time the important role of Survivin—a protein that has key ...

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS) and a common cause for neurological disabilities in young adults. Although it is known that the peripheral ...

Is the Tesla Model 3 a good car? The Tesla Model 3 is one of the best electric cars around. It’s practical, high-tech, and boasts great performance and range for a competitive price. The all ...