Toll-like receptors ... antigen-presenting cells and key cytokines. Furthermore, recent studies also have shown that TLR signaling can directly regulate the T cell activation, growth, differentiation, ...

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Recent data have shed some light on the mechanism by which IgL gene recombination is regulated by receptor signalling in developing B cells. The identification of the PI3K–PKB pathway as part of ...

Apart from its role in controlling signaling pathways downstream of BCR in mature B cells, Dok-3 has also been shown to be required for plasma cell ... Specifically, it is still not known if Dok-3 ...

Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors in the world, and its incidence and mortality have ...

Hepatocellular carcinoma (HCC) is one of the deadliest cancers globally, with increasing incidence and mortality rates.

Cells treated with ibrutinib and acalabrutinib each had a unique set of 13 m/z signals, which opens up the possibility of studying these metabolites as biomarkers of therapeutic response.

IntroductionHepatocellular carcinoma (HCC) is one of the deadliest cancers globally, with increasing incidence and mortality rates. It arises from ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...

A new study reveals that modifying the CUL5 gene enhances CAR-T cell therapy for leukemia and lymphoma. This improves cell ...

Therefore, it is important to understand how different cell signaling pathways impact inflammation to develop techniques to enhance neuronal survival and retinal regeneration. In this study we target ...