Introduction:Neutrophil transmigration is multifactorial and primarily driven by selectins and β 2-integrins (CD11b/CD18), whose expression are dependent on the underlying stimulus. Ventilator-induced ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

骨髓是人体造血的“工厂”，而骨髓增生异常肿瘤（MDS）则是这座工厂的“生产线故障”——血细胞发育异常，导致贫血、感染甚至白血病风险升高。

Suppression of antitumor immune responses is one of the main mechanisms by which tumor cells escape from destruction by the immune system. Myeloid-derived suppressor cells (MDSCs) represent the main ...

干细胞被称为医学界的“万用细胞”，因其具备自我更新和分化为多种细胞类型的能力，可用于修复和再生受损组织。它们在现代医学中发挥着重要作用，为疾病治疗和人类健康带来了新希望。间充质干细胞（MSC）因其来源丰富、安全性高，且具备免疫调节和 ...

ucl.ac.uk Results Dysregulated mitochondrial-associated gene expression correlated with increased ISG expression in JDM CD14+ monocytes. Altered mitochondrial-associated gene expression was paralleled ...

Jixin Zhong; Xiaoquan Rao; Jeffrey Deiuliis; Zachary Braunstein; Vimal Narula; Jeffrey Hazey; Dean Mikami; Bradley Needleman; Abhay R. Satoskar; Sanjay Rajagopalan ...

For cell sorting, pooled peripheral blood cells from either hTNFtg or WT mice were stained with CD11b, CD115 and Ly6-C antibodies and then isolated using a BD FACSAria II sorter. For in vitro OC ...

From the Center for Systems Biology (W.C.P., M.N., F.K.S.), Massachusetts General Hospital and Harvard Medical School, Boston. From the Center for Systems Biology (W ...

Following placement of skin allografts, donor DCs, often referred to as passenger leukocytes, migrate out of the graft through lymphatic vessels and infiltrate the recipient's draining lymph nodes ...