Research shows male microglia are more sensitive to disrupted CSF1R signaling, uncovering potential links to sex-based disparities in neurological disorders. Study: The microglial response to ...

Colony-stimulating factor 1 (CSF1) regulates microglia/macrophages proliferation, differentiation and survival thus, pharmacological treatments using CSF1 receptor (CSF1R) inhibitors had been used to ...

Circulating tumor DNA for predicting complete response to total neoadjuvant therapy in locally advanced rectal cancer: ENSEMBLE-2. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

This important study investigates the signaling pathways regulating retinal regeneration. Convincing evidence shows that the sphingosine-1-phosphate (S1P) signaling pathway is inhibited following ...

This important study provides insights into the physiological role of RIPK1 in liver physiology, particularly during short-term fasting. The discovery that RIPK1 deficiency sensitizes the liver to ...