Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...
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News Medical on MSNChanges to intermediate filament protein drives aggressive breast cancer growthChanges to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.
Knockdown of NOLC1 by siRNA decreased the protein level of the key stemness regulators MYC and ALDH and inhibited the sphere-forming capacity in TNBC cell line MDA-MB-231. Univariate and multivariate ...
Gliomas are known as an incurable brain tumor for the poor prognosis and robust recurrence. In recent years, a cellular subpopulation with tumor microtubes (TMs) was identified in brain tumors, which ...
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AZoLifeSciences on MSNMutant Vimentin Promotes Aggressive Breast Cancer GrowthVimentin is a type III intermediate filament (IF) protein typically expressed in cells that differentiate into connective ...
Scientists have uncovered a mechanism for reinvigorating the immune system to stop it from flagging when it’s fighting ...
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New research has found that changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth.
Announcing a new publication for Acta Materia Medica journal. Epithelial cell adhesion molecule (EpCAM) is a biomarker for epithelial cell-derived tumors. However, the specific role of EpCAM itself in ...
Feb. 7, 2025 — Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to ... Personalized Cancer ...
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