Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood ...
Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.
Collective cell migration is defined as the coordinated movement of multiple cells that retain cell–cell contacts while coordinating their actin dynamics and intracellular signalling.
In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...
Altogether, developing T cells migration, differentiation, maturation, proliferation, and survival are tightly regulated by a variety of hormones produced both locally and in other endocrine glands, ...
Collective migration plays critical roles in developmental, physiological and pathological processes, and requires a dynamic actomyosin network for cell shape change, cell adhesion and cell-cell ...
However, these alone cannot explain collective cell migration, and a large body of evidence suggests that movement may also happen in response to embryonic electrical fields. How and where these ...
After fasting, they found these cells had travelled to the pancreas. “Genetic photoconversion experiments revealed that fasting induced the migration of intestinal ILC2s to the pancreas ...
This study convincingly shows that aquaporin-mediated cell migration plays a key role in blood vessel formation during zebrafish development. In particular, the paper implicates hydrostatic pressure ...
In mechanobiology, cells' forces have been considered fundamental to their enhanced function, including fast migration. But a group of researchers in the McKelvey School of Engineering at ...
The Under-oil Open Microfluidic System enhances tumor cell-ECM interaction studies, improving anti-metastatic drug testing for triple-negative breast cancer.