In this review, we highlighted the influence on BCSCs exerted by different critical components and biochemical properties of ECM. The notion of cancer stem cells (CSCs) is garnering an increasing ...

The novel drug CT-179 ... How Healthy Stem Cells Turn Into Oral Cancer Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into ...

according to the American Cancer Society, and the rate of new cases continues to rise. Now, researchers at University of California San Diego have discovered how healthy stem cells are transformed ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

Recent studies have shown that the ECM augments tumor stiffness, interstitial fluid pressure, cell-to-cell junctions, and microvascularity using a mix of biomechanical and biochemical signals to ...

Stem cells are cells that have the capacity to self-renew by dividing and to develop into more mature, specialised cells. Stem cells can be unipotent, multipotent, pluripotent or totipotent ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity ...

D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

The ECM (extracellular matrix) provides the microenvironmental niche sensed by resident vascular smooth muscle cells (VSMCs). Aging and disease are associated with dramatic changes in ECM composition ...

We decipher subtypes of heterogenous cancer cells in primary CRC tissue, CRC liver and ovarian metastasis tissue, and profile characteristic for organ-specific CRC metastasis at single cell resolution ...