A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and ...

Theerawut et al. demonstrate that HA allows breast cancer cells to return to a stem cell state via EMT by modulating the TGF-β network (20). Recent studies have shown that using different molecular ...

Ephrin A1 facilitates colonization and metastasis of gastric cancer cells in vitro and in vivo via inducing epithelial-mesenchymal transition (EMT). Ephrin A1 directly interacts with EGFR and induces ...

Briefly, cancer cells were seeded at 0.15x10 6 cells/ml in 100 µl volume in a 96-well tissue culture ... Granulocyte macrophage colony stimulating factor; EMT, Epithelial-to-mesenchymal transition; PT ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Epithelial–mesenchymal transition triggered by epigenetic mechanisms can result in resistance to targeted therapies. Cancer stem cells form a self-renewing subpopulation of tumors and have been ...

By identifying key interactions between this common oral bacterium and host cells, the research ... bacterial infection and promote epithelial-mesenchymal transition (EMT), a process crucial ...