Scientists uncover biomarker for high risk of metastasis in multiple cancers
A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and ...
Nature1mon
Twisted epithelial–mesenchymal transition blocks senescence
The epithelial–mesenchymal transition (EMT) is a cellular transdifferentiation program that enables epithelial cancer cells to acquire traits of high-grade malignancy, notably invasive and ...
The EMBO Journal12d
Ephrin A1 functions as a ligand of EGFR to promote EMT and metastasis in gastric cancer
Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...
EurekAlert!2y
机械力传导促进肿瘤微球中间质样细胞引导的上皮样肿瘤细胞群体迁移和浸润
近日，北京大学工学院林峰博士在《中国科学：生命科学》杂志在线发表了题为“Mechanical transmission enables EMT cancer cells to drive epithelial cancer cell ...
Baylor College of Medicine1y
Chonghui Cheng Lab
Our work provided a conceptual understanding depicting a causal role for RNA alternative splicing in EMT and breast cancer recurrence. We found that splice isoform switching of the CD44 gene must take ...