Summary: A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views on aging. Researchers found that random genetic mutations drive ...

Cisplatin-based neoadjuvant chemotherapy (NAC) followed by radical cystectomy (RC) or chemoradiotherapy (CRT) is the standard ...

In a family of 15 people in northern Italy, six developed late-onset Alzheimer’s disease – and when researchers ran genetic tests, all six had a rare mutation in a protein-coding gene known as ...

Variations at ERCCI and ERCC2 enhance response to platinum chemotherapy but their overexpression will reduce patient survival with gemcitabile-cisplatin treatment. The advanced chemotherapy for tumors ...

Patients with XP have constitutional inactivating mutations in both alleles of certain genes that encode DNA repair proteins, in particular those involved in nucleotide excision repair ...

Black fur comes from a genetic mutation that was likely in domesticated dogs thousands of years ago. The dark fur is rare in Europe due to a reduced genetic diversity, but at least half of the ...

Test your knowledge of this quiz on the Canadian Urological Association's recommendations for genomic profiling of tumors in prostate cancer.

Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.

While the virus is generally found in wild birds and poses risk only to poultry, its spread to a new range of mammals may pave the way for new mutations that could increase its lethality. In 2024, the ...

Feb. 7, 2025 — A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 ...

Gene sequencing of these D1.1 viruses has found a mutation that helps the virus copy itself more efficiently into the cells of mammals, including people. This change hasn’t been seen in other D1 ...