Even more fascinating is the intricate relationship between lysosomal exocytosis and focal adhesions, structures critical for cell anchoring and communication. By decoding how focal adhesions ...

Intercellular adhesion can be mediated by adherens junctions, tight junctions and desmosomes, whereas cells can interact with extracellular matrix molecules through focal adhesions ...

Mechanobiology Institute Singapore, National University of Singapore, Singapore 117411, Singapore ...

During cell elongation, clusters of focal adhesions (FAs) form near the poles of the elongating cells. FAs are mechanosensitive clusters of adhesions that grow under mechanical tension exerted by the ...

Polymorphonuclear leukocytes have been implicated in the development of the "no-reflow" phenomenon after focal cerebral ischemia and reperfusion. To further understand the role of granulocytes in ...

Department of Nephrology, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu 610041, China College of Polymer Science and Engineering, College of Biomedical Engineering, State ...

In culture, most cells develop sites of adhesive interaction--known as focal adhesions--with ECM molecules that are adsorbed to the underlying plastic or glass surface. At their cytoplasmic face, ...

They serve as anchoring points for the cells. Every cell has many of these anchoring points, called focal adhesions, which give the cell support like little feet. Integrins have to cooperate with ...

In a report released today, Graig Suvannavejh from Mizuho Securities reiterated a Buy rating on Verastem (VSTM – Research Report), with a price ...

Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced its 2025 priorities and upcoming ...