Researchers are studying a new approach to HDFN prevention to reduce cases in countries where incidence rates remain high.

lumc.nl Objective To determine whether anticitrullinated protein antibodies (ACPA) exhibit specific changes in Fc glycosylation prior to the onset of arthritis. Methods Serum samples of patients with ...

using antibody expression system, transformation of host cell lines, and glycosylation modification. Finally, the authors discuss the potential of large-scale production of recombinant antibodies and ...

This review summarizes recent progress in both natural and engineered structural modifications of IgG antibodies, including allotypic variation, glycosylation, Fc engineering, and Fc gamma receptor ...

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments for diseases such as cancer, Alzheimer's disease, autoimmune disorders and ...

Antibodies and related products are the fastest growing class of therapeutic agents. By analysing the regulatory approvals of IgG-based biotherapeutic agents in the past 10 years, we can gain ...

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

IgG inhibition of a monoclonal antibody therapy can help with the selected deactivation of serum IgG with EndoS. Peptide glycosylation can be achieved using a two-step process involving EndoA or ...

Changes in glycosylation are often associated with ... intracellular sialic acid levels is untenable by current lectin or antibody methods. In a cellular model system these mutations can be ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

Different types of antibodies are produced by your immune system. These five antibodies help fight disease by detecting viruses, bacteria, and other pathogens (disease-causing microorganisms) and ...