IL-11 promotes the development of hypertension and may also be associated with the ERK pathway. As discussed in the text, the expression of IL-11 and IL-11RA was upregulated in the pulmonary artery ...

Pathological alterations of this vessel wall architecture called vascular remodeling can lead to insufficient vascular function and subsequent ischemia and organ damage. One major pathomechanism ...

One potentially serious complication of obstructive sleep apnea (OSA) is pulmonary hypertension (PH). Based on previous research that revealed involvement of perivascular immune and inflammatory ...

The following is a summary of “Development of the pulmonary fibrosis, pulmonary vascular resistance, six minute walk distance, B-type natriuretic peptide, age (PVD-B65) risk score for patients with ...

In this study, we demonstrate that PGRN can have a negative impact on vascular remodeling and aortic contractility ... the mechanisms by which PGRN affects capacitance versus resistance arteries, and ...

Adequate Sleep Significantly Reduces the Risk of Hypertension in Adolescents Nov. 11, 2024 — Adolescents who meet the recommended guidelines of nine to 11 hours of sleep per day were shown to ...

F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression. This approach ...

"We know that during the remodeling process fibroblasts are activated," said Cheng Hong, MD, Ph.D., pulmonary vascular medicine ... in Pulmonary Arterial Hypertension, Journal of Nuclear Medicine ...

These conditions mimic post-menopause hypertension and hormonal replacement therapy ... (5) The authors claim (or hypothesize) that the reduced AABA level in OVX can cause vascular remodeling. This ...