Severe renal fibrosis often occurs in obstructive kidney disease, not only in the obstructed kidney but also in the contralateral kidney, causing renal dysfunction. Although the mechanisms of injury ...

Acute kidney injury (AKI) is a common critical clinical disease that is linked to significant morbidity, recurrence, and mortality. It is characterized by a fast and prolonged loss in renal function ...

The genetic disorder cystic fibrosis is unique because it can cause both breathing and digestive problems. Some 40,000 people in the U.S. currently have it, "though this is likely an ...

Kidney stones are pebble-sized deposits that form when there’s too much salt and minerals in your urine. Learn whether men or women are more at risk, what passing one feels like, and how big ...

Most cancers are named after the part of the body where the cancer first begins, and kidney cancer is no exception. Kidney cancer begins in the kidneys—two large, bean-shaped organs—one located to the ...

and fibrosis in MCD-fed mice. Furthermore, SOX9 deletion inhibited AMPK pathway activation, while SOX9 overexpression enhanced it. Notably, administration of an AMPK inhibitor negated the ...

Department of Nephrology, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu 610041, China College of Polymer Science and Engineering, College of Biomedical Engineering, State ...

Learn about cystic fibrosis, a genetic disorder that affects the lungs ... As doctors suggested unlikely diseases, such as hormonal disorders, kidney disease, lupus, and depression, I felt I was ...

In its early stages, kidney disease may not cause any symptoms or signs. However, as it progresses, it can cause symptoms such as itchy skin, pruritus, and a rash. Around 35.5 million adults in ...

Several risk tools can accurately predict individual baseline risks of adverse events in people with chronic kidney disease. Here, the authors examine methods of assessing risk and discuss risk ...

iDivision of Nephrology, Department of Medicine, O'Brien Institute for Public Health, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada jDepartment of Community Health Sciences, O ...