Researchers have identified a key role microglia play in melanoma brain metastases progression and mechanisms to target them.
Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...
Researchers suspected that microglia could also break down amyloid plaques, but it was unclear how the cells could consume these massive aggregates, which are much bigger than they are. "We found ...
Scientists from DZNE, University Hospital Bonn, and the University of Bonn have found new evidence that reducing brain inflammation could help treat Alzheimer’s disease. Their research, published in ...
Wu and colleagues confirmed that cultured-microglia-carrying lipid droplets struggled with phagocytosis, poorly engulfing ...
Microglia, the brain's immune cells, exhibit altered gene expression and a weakened immune response as they age, potentially contributing to neurological disorders like Alzheimer's and Parkinson's.
Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small fragments called micronuclei produced by neuronal nuclei are released into ...
The study, published today in Cancer Cell, demonstrates that microglia, a type of resident immune cell in the brain, can be ...
Researchers have found that a lifelong diet rich in choline could help protect against Alzheimer’s disease. Choline is an ...
Pexidartinib or PLX3397 is an enzyme inhibitor commonly used to remove microglia in the lab setting to help researchers better understand the role of these cells in brain health, function ...