Organoids were maintained in spinning culture, and media was changed every 3–4 days until experimental endpoints ... Additionally, our protocol incorporates microglia to more fully recapitulate the ...

Summary: Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive. New research ...

With the ANN-based NAD(P)H FLIM analysis approach, we found that microglia in cell culture mixed with other glial cells can be identified with more than 0.9 True Positive Rate (TPR). We also extended ...

During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...

Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small fragments called micronuclei produced by neuronal nuclei are released into ...

Their findings, based on studies in cell culture, mice and tissue samples from patients ... Specifically, we pharmacologically manipulated a molecular complex called the NLRP3 inflammasome. It is ...

Although most leaders recognize the importance of organizational culture in driving business performance, many struggle to truly understand their culture and implement effective change when needed.

Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan Division of Molecular Neuroimmunology, Medical Institute of Bioregulation ...