Their variable regions bind targets with ... for exploring the vast combinatorial space of antibody sequences. By integrating data on binding, structure, and activity, AI can usher the transition ...

Current bispecific antibody development does not involve testing in chimpanzees, an endangered species. Medarex also developed Nivolumab, an antibody targeting a second T cell inhibitory molecule PD1, ...

It seeks to explain biological function in terms of molecular structure, dynamics and organization, from single molecules to supramolecular structures. Here, the authors use cryo electron ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...

Chemical Engineering is concerned with the design and operation of processes which convert materials and energy into the higher value products we use every day. It understands the processes which ...

The trend for Tampa Bay demonstrates a steady upward trajectory over the past decade, achieving a first place ranking in 2019 compared to other regions. This indicator represents the total number of ...

Feb. 14, 2025 — The process of separating useful molecules from mixtures of other substances accounts for 15% of the nation's energy, emits 100 million tons of carbon dioxide and costs $4 ...