FIGURE 3. Basic structure of antibody. Each IgG antibody molecule consists of four polypeptide chains (two identical light chains and two identical heavy chains joined by disulfide bonds) and has two ...

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal antibodies are derived from hybridoma technology, the recombinant antibodies are ...

Their variable regions bind targets with ... for exploring the vast combinatorial space of antibody sequences. By integrating data on binding, structure, and activity, AI can usher the transition ...

might stand on a different footing from a material such as ordinary glass built up by chemical action and formation of complex silicates.

which provides the general region of the target protein the antibody binds to. With the advent of widely available chemical peptide synthesis, sequence-specific synthetic peptides can be used for ...

Current bispecific antibody development does not involve testing in chimpanzees, an endangered species. Medarex also developed Nivolumab, an antibody targeting a second T cell inhibitory molecule PD1, ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

The new structure incorporates chemical groups called sulfonates to make it compatible with water, allowing it to function in real-world water systems, like rivers or wastewater. It uses a natural ...

Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...