This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

In the intricate science of reproduction, the creation of offspring has long relied on the union of sperm and eggs, whether ...

Germline development is the development of the cell lineage that gives rise to the reproductive cells, called gametes, of sexually reproducing organisms. Primordial germ cells, the founder cells ...

Colossal has also altered the DNA sequence in chicken primordial germ cells (PGCs), injected them into embryos, and successfully hatched chimeric chicks. Their offspring will be surrogates for dodos.

The World Economic Forum predicts that biodiversity loss could cause a colossal decline in global GDP of $2.7 trillion ...

Our new president has been awfully busy this past week. In his first 10 days in office, Donald Trump has signed more than three dozen executive orders and reversed several ...

"The dodo project is more challenging due to the need to reach primordial germ cells in pigeons first," said Lamm. These germ cells are specialized cells that produce an animal's reproductive cells.

Both male and female genitalia differentiate from the same structures along the urogenital ridge. At about 4 weeks after fertilisation, primordial germ cells migrate from the yolk sac wall to the ...