The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...

Isomorphic Labs, a spin-off from DeepMind, is applying AI-first principles to drug discovery rather than just protein ...

The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics, has ...

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

School of Information Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Pudong New Area, Shanghai 201210, China Shanghai Institute for Advanced Immunochemical Studies, ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

This asymmetry in the native structure of transthyretin also presents a hypothesis for how the process of dissociation and misfolding could occur, then lead to the clumping of the protein and ...

"A key feature of our method is blind docking, which predicts how the redesigned protein interacts with its ligand without the need for predefined binding site information," Hy said. "This ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

Insulin-like Growth Factor-Binding Protein 7 (IGFBP7) is an extracellular matrix (ECM) glycoprotein, highly enriched in activated vasculature during development, physiological and pathological tissue ...