Apart from these studies on regulatory RNAs, recent genome-wide research also reveals the general role of mRNA structure in a variety of post-transcriptional regulations such as RNA maturation, RNA ...

Figure 1: Secondary structures of RNA stem-loops that bind to MS2 coat protein. Figure 2: Overall structure of the complexes, generated by superposing the coat protein. Figure 4: Schematic diagram ...

an RNA structure normalization tool used in RNA-Puzzles. the RNA 3D structure comparison metrics used in RNA-Puzzles assessment, including RMSD (all-atom), P value, Interaction Network Fidelity and ...

Circular RNA is essentially a single-stranded RNA molecule with a closed- loop structure that does not code for any protein ... and SiTu Editing in the Marrow (STEM), which targets stem cells in the ...

In eukaryotic cells, RNA polymerase II synthesizes mRNA in three stages ... Using embryonic fibroblasts cultured from two knock-in mouse models, we monitored transcription of β-actin and Arc mRNA ...

Another important discovery was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus to produce the correct ...

Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, United States Department of Biochemistry and Structural Biology, University of ...

In human cancers, aberrant post-transcriptional modifications, such as alternative splicing and RNA editing, may lead to tumour specific transcriptome diversity. Design By utilising large scale ...

Currently, no approved treatments exist. To address this ... How Healthy Stem Cells Turn Into Oral Cancer Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that ...

This is where DNA and RNA epigenetics comes in ... for example in embryonic stem cells. This combination offers incredibly precise regulation of gene activity, essential to the development ...

The novel drug CT-179 ... How Healthy Stem Cells Turn Into Oral Cancer Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into ...