This important study addresses the idea that defective lysosomal clearance might be causal to renal dysfunction in cystinosis. With mostly solid data, the authors observe that restoring expression of ...

A more efficient way to extract fertiliser from human urine could help make better use of wastewater in cities and farms, without exacerbating global warming. Human urine is rich in compounds ...

Microscopic examination of the urine sediment for renal tubular epithelial cells, granular casts, and cellular casts helps diagnose specific parenchymal kidney diseases causing AKI. High interoperator ...

In recent years, several developments have been made in the field of DNA damage. Herein, we review the roles and developments of DNA damage and DNA damage response in renal tubular epithelial cell ...

In the present study, we explored whether senescent renal tubular cells promote renal tubulointerstitial fibrosis by secreting Sonic hedgehog (Shh) which mediates fibroblast activation and ...

The developmental mechanisms underlying P-D axis patterning in epithelial tubules are not well understood for any organ. The insect renal (or Malpighian) tubule is a relatively simple epithelial ...