Nanotechnology-mediated tumor vascular targeting. Tumor blood vessels are mainly composed of endothelial cells and pericytes. A variety of angiogenic receptors are expressed on tumor-associated ...

The next step is to figure out how to keep this receptor switched on, so that the tumour cells can’t leave the blood vessels ... analusis of tumor-endothelial signalling identifies EPHA2 as a negative ...

Water flow plays a surprising role in the formation of new blood ... cell migration during development in zebrafish. "How endothelial cells migrate is very important because new blood vessels won ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Endothelial cells aid tumors in forming the blood vessels that transport nutrients to tumor cells ... To confirm that protein transfer isn’t limited to cultured cells, the team injected cancer cells ...

By replicating conditions like tissue stiffening and scarring—common in aging, chronic diseases and cancer—the researchers discovered that perivascular cells drive blood vessel leakage and ...

The curvature of a surface determines the migration ... and cancer cells migrate through the body, causing metastasis. Inside the body, many surfaces, such as tissues, blood vessels, or ...

Brain tumors often rely on blood vessel cells, also known as vascular endothelial cells, to fuel their growth. These tumor blood vessels not only supply oxygen and nutrients, but also produce ...

known as perivascular cells, contribute to blood vessel dysfunction in chronic diseases such as cancer, diabetes and fibrosis. The findings, published today in Science Advances, could change how these ...